Primaire amoebenmeningitis (PAM)
Bronnen
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Pubmed.gov publication # 25445746
Baig AM, Khan NA (2015) Tackling infection owing to brain-eating amoeba. Acta Trop. 142:86-8
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Pubmed.gov publication # 30358879
Colon BL, Rice CA, Guy RK, Kyle DE (2019) Phenotypic Screens Reveal Posaconazole as a Rapidly Acting Amebicidal Combination Partner for Treatment of Primary Amoebic Meningoencephalitis. J Infect Dis. 219:1095-1103
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Pubmed.gov publication # 26582886
Capewell LG, Harris AM, Yoder JS, Cope JR, Eddy BA, Roy SL, Visvesvara GS, Fox LM, Beach MJ (2015) Diagnosis, Clinical Course, and Treatment of Primary Amoebic Meningoencephalitis in the United States, 1937-2013. J Pediatric Infect Dis Soc. 4:e68-75.
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Pubmed.gov publication # 32513800
Sarink MJ, Tielens AGM, Verbon A, Sutak R, van Hellemond JJ (2020) Inhibition of Fatty Acid Oxidation as a New Target To Treat Primary Amoebic Meningoencephalitis. Antimicrob Agents Chemother. 64:e00344-20.
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Pubmed.gov publication # 35861895
Martinez et al. (2022) Successful Treatment of Primary Amoebic Meningoencephalitis Using a Novel Therapeutic Regimen Including Miltefosine and Voriconazole. Acta Parasitol. 67(3):1421-1424
Categorie
Metadata
Swab vid: G-499839.3
Bijgewerkt: 12/29/2023 - 15:24
Status: Published
Algemene opmerkingen
1e keuze:
conventioneel amfotericine B (fungizone) 1,5mg/kg/dag iv +/- intrathecaal
+
rifampicin 1dd 10mg/kg/dag iv (of in 3 dosis po)
+
fluconazol 12mg/kg/dag iv of po
+
miltefosine <45 kg: 2dd 50mg po
>45 kg: 3dd 50mg po
+
azitromycine 1dd 500mg iv of po
+
steroïden om cerebraal oedeem te voorkomen / beperken