Cryptosporidiose - Cryptosporidium species
Advices
Priority | Medication | Remarks |
---|---|---|
Priority: 1st choice |
Remarks:
|
|
Priority: 2nd choice |
Medication: nitazoxanide po 500/1000mg 2dd 21 days |
|
Priority: 3rd choice |
Medication: paromomycine po 500mg 4dd 21 days +
azitromycine po 500mg 1dd 21 days |
Sources
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http://aidsinfo.nih.gov/guidelines
Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents
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Pubmed.gov publication # 19632225
Rossignol JF (2010) Cryptosporidium and Giardia: treatment options and prospects for new drugs. Exp Parasitol. 124:45-53.
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Pubmed.gov publication # 12814654
Mele R et al 2003 Indinavir reduces Cryptosporidium parvum infection in both in vitro and in vivo models. Int J Parasitol. 2003 Jul;33(7):757-64.
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Pubmed.gov publication # 25278220
Checkley W, White AC Jr, Jaganath D, et al. A review of the global burden, novel diagnostics, therapeutics and vaccine targets for Cryptosporidium. Lancet Infect Dis. 2015;15(1):85-94.
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Pubmed.gov publication # 20689422
Cabada MM, White AC. Treatment of cryptosporidiosis: do we know what we think we know? Curr Opin Infect Dis. 2010;23(5):494-499.
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Pubmed.gov publication # 19400754
Pantenburg B, Cabada MM, White AC jr. (2009) Treatment of cryptosporidiosis. Expert Rev Anti Infect Ther 7: 385-91.
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Pubmed.gov publication # 18641847
Bachur TP et al 2008 Enteric parasitic infections in HIV/AIDS patients before and after the highly active antiretroviral therapy. Braz J Infect Dis. 12(2):115-22.
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Pubmed.gov publication # 17335543
Abubakar I, et al. Treatment of cryptosporidiosis in immunocompromised individuals: systematic review and meta-analysis. Br J Clin Pharmacol. 2007;63:387-393.
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Pubmed.gov publication # 11049793
Cochrane Database Syst Rev. 2007;24:CD004932. Hewitt RG, et al. Paromomycin: no more effective than placebo for treatment of cryptosporidiosis in patient with advanced human immunodeficiency virus infection. Clin Infect Dis. 2000;31:1084-1092.
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
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Metadata
Swab vid: G-376971.4
Updated: 12/01/2023 - 17:19
Status: Published
General comments
Bij HIV:
Paromomycine
Nitazoxanide