sepsis - Stenotrophomonas maltophilia
Advices
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: cotrimoxazol (trimethoprim +sulfamethoxazol) iv 1920mg 3dd or
cotrimoxazol (trimethoprim +sulfamethoxazol) po 1920mg 3dd |
Sources
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Pubmed.gov publication # 10639352
Multiple antibiotic resistance in Stenotrophomonas maltophilia: involvement of a multidrug efflux system. Zhang L1, Li XZ, Poole K. Antimicrob Agents Chemother. 2000 Feb;44(2):287-93.
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Pubmed.gov publication # 9124855
Stenotrophomonas maltophilia: emergence of multidrug-resistant strains during therapy and in an in vitro pharmacodynamic chamber model. Garrison MW1, Anderson DE, Campbell DM, Carroll KC, Malone CL, Anderson JD, Hollis RJ, Pfaller MA. Antimicrob Agents Chemother. 1996 Dec;40(12):2859-64.
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Pubmed.gov publication # 35439291
Infectious Diseases Society of America 2022 Guidance on the Treatment of Extended-Spectrum β-lactamase Producing Enterobacterales (ESBL-E), Carbapenem-Resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with Difficult-to-Treat Resistance (DTR-P. aeruginosa). Tamma PD, Aitken SL, Bonomo RA, Mathers AJ, van Duin D, Clancy CJ.Clin Infect Dis. 2022 Aug 25;75(2):187-212.
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
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Metadata
Swab vid: G-148526.6
Updated: 06/06/2023 - 14:04
Status: Published
General comments
Duur afhankelijk van het focus van de infectie.
Ook bij bewezen gevoeligheid is cotrimoxazol de eerste keus aangezien er vanuit de literatuur aanwijzingen zijn dat de kans op selectie van resistentie tijdens therapie groter is bij het gebruik van levofloxacin.