malaria tertiana (Plasmodium vivax / ovale)
Advices
Priority | Medication | Remarks |
---|---|---|
Priority: 1st choice |
Medication: chloroquine po 600mg 1dd 2 days followed by
chloroquine po 300mg one-off |
Remarks:
Cave: chloroquine resistente P. vivax ZO-Azië |
Priority: 2nd choice |
Medication: artemether/lumefantrine po 80/480mg dd |
Remarks:
dosis (=4 tabletten a 20/120mg) op t=0, 8, 24, 36, 48, 60, 72, 84, 96 & 108 uur. 1e keuze bij chloroquine resistente P. vivax uit ZO Azie. |
Priority: 2nd choice alternative |
Medication: atovaquon+proguanil po 1000/400mg 1dd 3 days |
Remarks:
dosis = 4 tabletten a 250/100mg |
Priority | Medication | Remarks |
---|---|---|
Priority: 1st choice |
Medication: chloroquine po 600mg 1dd 2 days followed by
chloroquine po 300mg one-off |
Remarks:
Cave: chloroquine resistente P. vivax ZO-Azië |
Priority: 2nd choice |
Medication: artemether/lumefantrine po 80/480mg dd |
Remarks:
dosis (4 tabletten a 20/120mg) op t=0, 8, 24, 36, 48, 60, 72, 84, 96 & 108 uur 1e keuze bij chloroquine resistente P. vivax uit ZO Azie. |
Priority: 3rd choice |
Medication: quinine po 600mg 3dd 7 days +
clindamycine po 5mg/kg 3dd 7 days |
Priority | Medication | Remarks |
---|---|---|
Medication: primaquine po 30mg 1dd 14 days |
Remarks:
= nabehandeling (voorkomt recidief) |
Sources
-
https://reliefweb.int/report/world/who-guidelines-malaria-25-november-2022
WHO guideline for the treatment of malaria
-
Pubmed.gov publication # 28369315
Neumayr A, et al.. Artemether-Lumefantrine Treatment Failure in Nonimmune European Travelers With Plasmodium falciparum Malaria: Do We Need to Reconsider Dosing in Patients From Nonendemic Regions? Clin Infect Dis. 2017 May 15;64(10):1466-1467.
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
- chloroquine
- atovaquon+proguanil
- artemether/lumefantrine
- quinine
- clindamycine
- primaquine
External antimicrobial resources
Menu position
Metadata
Swab vid: G-147880.9
Updated: 01/16/2025 - 18:44
Status: Published
General comments
Behandeling malaria altijd in overleg met consulent tropenziekten.
Bij zeer ernstige presentatie, overweeg behandelen als ernstige malaria tropica.
Resistente P. vivax in ZO-Azië
Chloroquine:
Artemether/lumefantrine
Atovaquone /proguanil:
Primaquine
Meldingsplichtige ziekte groep C